Search by tag «Publication» 157 results

  • First in the World: ITMO Researchers Train DNA Constructs to Detect Cancer Cells Based on Cancer Marker Concentration

    Researchers from ITMO University have developed DNA constructs based on antisense oligonucleotides that can detect different cancer marker concentrations in cells. Thanks to this capability, the DNA constructs activate only in cancer cells with high concentrations of cancer markers, cleaving the RNAs of genes responsible for the cells’ viability. At the same time, healthy cells, even with several copies of cancer markers inside, remain untouched. With this solution, target cancer therapy will become more accurate, efficient, and safe. The new DNA constructs were described in a paper published in Chemical Communications. 


  • ITMO’s New Compound Disables Disease-Producing Genes 17 Times Faster Than Counterparts

    Scientists from ITMO University have created a new compound – bivalent DNAzymes: these are short, connected therapeutic DNA chains. The compound has four “arms” and two cores that enable it to find the target sequence even in the complex twisted messenger RNA of a gene, then bind with this site, and cleave it. Among the solution’s possible applications are new treatments for viral, oncological, and hereditary diseases at early stages. The DNAzyme was described in a paper published in Nucleic Acids Research.


  • New by ITMO Scientists: Digital Service to Facilitate Artificial Enzymes for Industry and Medicine

    Researchers from ITMO University have developed a web platform that is capable of predicting a nanozyme’s (artificial enzyme) capability to accelerate chemical reactions – with high accuracy and in mere seconds. Apart from being free, the platform is user-friendly, as it’s equipped with a ChatGPT-based assistant. Among its applications is the development of new cancer treatments and sensors of hazardous materials. The platform was described in a paper published in The Journal of Physical Chemistry Letters.


  • ITMO Researchers Use Hybrid Crystal to Enable Simultaneous Grayscale and Color Direct Laser Writing

    With the new material suggested by ITMO physicists, it will be possible to embed grayscale images into color ones during direct laser writing. The researchers were the first to use metal-organic frameworks for the purpose; these are optically transparent materials that can transform laser radiation. When subjected to it, the material’s structure changes, with color defects formed inside. Each such defect has a unique scattering spectrum, making metal-organic frameworks useful in producing uncloneable anti-counterfeit trademarks. The material is described in a paper published in Advanced Functional Materials.


  • ITMO Experts Confirm: Electrical Cardioversion Safe to Conduct at Smaller Clinics

    Researchers from ITMO University have demonstrated that electrical cardioversion, a procedure that helps “reset” an abnormal heart rhythm, can be safely and effectively conducted at community hospitals to treat atrial fibrillation. A paper describing the results of the study was published in BMC Cardiovascular Disorders.


  • Longer-Lived Quantum States Suggested at ITMO

    Physicists from ITMO University have created an AI-based solution to make quantum states remain stable for longer for the processing, reliable recording, and storage of information. This study, described in a recent article in Applied Physics Letters, may help pave the way to quantum computers.


  • ITMO Scientists Suggest Platform to Study Cell Communication and Assist Targeted Drug Delivery

    Researchers from ITMO University have developed a platform that will help study extracellular cell communication. Unlike its counterparts, the new platform can identify the precise location of cells without interrupting their function – this way, it’s possible to observe cells in their natural state. This solution will facilitate rehabilitation of cell communication after injuries and help create materials for targeted drug delivery. The new platform is described in an article published in Materials & Design.


  • ITMO Researchers Discover Connection Between Gut Microbiome and Melanoma Treatment

    Having analyzed metagenome data from hundreds of microbiome samples, scientists from ITMO University have found out how the composition of the gut microbiome affects the efficacy of melanoma treatment. In the future, the discovered link can be used to develop treatment plans for cancer patients, as well as improve the efficacy of melanoma treatment. The results of the research are described in a paper published in Life Science Alliance.


  • ITMO Solution Prevents Counterfeiting of Glass Products

    Researchers from ITMO University have suggested a method of creating colored patterns with an affordable, domestically-produced laser. Compared to others, the new method makes it possible to create smaller separate patterns within a single bigger one, which are harder to forge. The technology, described in an article published in Optics and Laser Technology, will help prevent production of counterfeit glass products, such as medical vials and test tubes.  


  • ITMO Scientists Unveil Algorithm to Predict Properties of Organic Solvents

    The staff of ITMO’s Center for AI in Chemistry have designed a free service that predicts properties of organic solvents. These substances find their applications in pharmaceutical, oil, and cosmetics industries. The research behind the algorithm is described in a paper published in Green Chemistry.