Search by tag «Mice» 2 results

• Scientists Create Listeriosis-Immune Mice by Turning off Gene in Myeloid Cells

  An international research team that includes specialists from ITMO University has conducted a series of experiments with the goal of studying the immune system and identifying the genes and proteins involved in the response to certain harmful bacteria. The scientists found that “turning off” a gene responsible for the production of the protein Beclin 1, or the gene that produces the FIP200 protein, resulted in the test animals becoming nearly completely immune to the infectious disease listeriosis. The results of this research have been published in Nature Microbiology.

  22.01.2020

• Scientists Develop Improved Model for Study of Zika Virus

  An international research team has developed a new animal model used to study the pathogenesis of the Zika virus. Scientists were able to make the disease develop in mice in a way that is similar to what happens in humans. The new model reflects the most dangerous manifestation of the Zika virus: infection of the fetus from a pregnant woman, which leads to developmental problems. Such an advancement was achieved due to a new, more pathogenic virus strain, as well as a specially bred group of mice with a human-like immune response. The new model paves the way for more detailed study of the Zika virus, which should result in a more effective fight against it. The research is published in Cell Host & Microbe.

  24.05.2018