Search by tag «Targeted Drug Delivery» 13 results

• Building A New Generation of Drugs: SCAMT Laboratory Scientists On Rational Chemical Design Using Metal-Organic Frameworks

  Aimed at creating materials with pre-planned properties, rational design has become one of the most prevalent research trends in chemistry. Its advocates postulate that instead of going through the exhaustive search of random combinations, a better strategy for finding the right material would be to start with analysing the structural elements and the interactions that occur between them. This will lead to significant reductions in the effort, time, and money needed for creating new drugs or purification systems. Following their paper on framework materials that was published in Russian Chemical Reviews, ITMO University’s SCAMT Laboratory scientists met with ITMO.NEWS to talk about their research.

  03.08.2018

• Scientists Describe Oxidants' Effect on Metal-Organic Frameworks for Drug Delivery

  A team of chemists-theoreticians modeled the interaction of a metal-organic framework (MOF) for drug delivery with oxidants. The model showed that the MOF is stable in water, but degrades in the presence of active forms of oxygen. As such oxidants emerge in inflammatory tissues, MOFs can be used in the design of systems for targeted delivery of anti-inflammatory agents. The research results were published in The Royal Society of Chemistry (PCCP) magazine.

  27.06.2018

• ITMO Researchers Participating in Targeted Drug Delivery Research

  Targeted delivery of medicine and genetic material to cells and tissue can be solved using micro- and nanoparticles of various types. Research in this field tends to be interdisciplinary and calls for collaboration between biologists, chemists and physicists. Mikhail Zyuzin, a postdoctoral researcher at ITMO University’s Faculty of Physics and Engineering, is working with colleagues from Russia and abroad to develop new methods of targeted drug delivery. He spoke with ITMO.NEWS about his research and working with other scientists.

  28.02.2018