Search by tag «Nucleic Acids Research» 2 results

• ITMO’s New Compound Disables Disease-Producing Genes 17 Times Faster Than Counterparts

  Scientists from ITMO University have created a new compound – bivalent DNAzymes: these are short, connected therapeutic DNA chains. The compound has four “arms” and two cores that enable it to find the target sequence even in the complex twisted messenger RNA of a gene, then bind with this site, and cleave it. Among the solution’s possible applications are new treatments for viral, oncological, and hereditary diseases at early stages. The DNAzyme was described in a paper published in Nucleic Acids Research.

  11.06.2024

• How Computer Algorithms Help Study Metabolic Processes on the Deepest Level

  Scientists from ITMO’s International Laboratory “Computer Technologies” have launched GATOM, a new version of their online service GAM (Genes and Metabolites). The platform analyzes the gene expression and cell processes, as well as looks for the connections between them. This helps researchers figure out how, for instance, the cells of an immune system function. The scientists are confident that their tool will not only help better understand biological processes at the cellular level but also benefit the development of treatment for autoimmune diseases and cancer. 

  14.06.2022