Search by tag «Preclinical studies» 2 results

  • New Magnetically Controlled Thrombolytic Successfully Passed Preclinical Testing

    New anti-thrombosis drug based on magnetite nanoparticles and developed at ITMO University has been successfully tested on animals. Preclinical studies conducted as part of the project "PHARMA 2020" showed the drug’s high efficacy and no side effects, with the clot dissolution rate being twenty times shorter than that of traditional medications. The range of permissible concentrations is very high, and the minimum dose of the active substance required to achieve the desired effect was a hundred times smaller than usual. The results are published in Applied Materials and Interfaces.


  • Researchers Developed Effective MR Coil for Preclinical Studies

    Researchers from ITMO University developed and tested an MR coil for high-quality imaging of the whole mouse. Such coils are required for preclinical studies of drugs, as well as for targeted examination of various body systems. Due to the design features, the new coil provides three times higher image quality than a commercial volume MR coil, usually used in such studies. The coil is low-cost and the manufacturing technology can be adapted for different studies. It was experimentally studied in collaboration with researchers from the Moscow State University. The research was published in the journal NMR in Biomedicine and sited on the cover of the issue.