Search by tag «mSystems» 2 results

  • Gut Microbiota Can Predict Immunotherapy Response, ITMO Scientists Say

    In their study of correlations between intestinal microbiota and melanoma treatment results, researchers from ITMO University and the Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine have come across functional biomarkers that can predict immunotherapy efficacy and beneficial bacteria that enhance immune responses in patients through stimulating the development of T-cells. The findings can be potentially used to develop a pre-treatment diagnostic test and issue recommendations for gut microbiome correction. The results of the study were published in mSystems.


  • ITMO Researchers Create Model to Demonstrate What Happens During Microbiota Transplantation Genome-Wise

    Fecal microbiota transplantation (FMT) has been successfully used in treating metabolic and intestinal diseases. Even though the procedure shows high effectiveness, its mechanism remains unclear. To that end, scientists from ITMO University and the Federal Research and Clinical Center of Physical-Chemical Medicine (Russian Federal Medical Biological Agency) carried out an extensive study on post-FMT patients, during which they figured out how the intestinal microbiota changes under FMT and how its composition correlates with donor microbiota.