Search by tag «Targeted Drug Delivery» 13 results

  • ITMO Researchers Produce Magnetic Spider Silk-Based Structures for Implantology and Targeted Drug Delivery

    Scientists from ITMO University have created a magnetic material capable of promoting tissue regeneration by utilizing silk of the Linothele fallax spiders, which holds promise for implantology and tissue regeneration. In the material, the silk makes up a scaffold for cell growth, while the medications, which reach the target under the influence of the magnetic field, accelerate recovery. The drug was successfully tested in vitro – and described in International Journal of Biological Macromolecules.


  • ITMO's Monday Science Roundup #6

    We’re back with another selection of the past two weeks’ top news from the world of science! This time, we’ve got not one, not two, but three research breakthroughs – along with an exciting new Master’s program for AI enthusiasts.


  • ITMO Researchers Develop Method for Production of Hollow Nanoparticles From Liquid Metal

    Hollow nanocapsules are widely used for various purposes: from targeted drug delivery to catalytic reactions in petrochemistry. An article on the method was published in Chemistry of Materials.


  • ITMO Associate Professor Elena Koshel on What DNA Robots Could Mean for Medicine

    During the third scientific meetup in a recently-introduced series, Elena Koshel, an associate professor at ITMO University’s ChemBio Cluster and head of the Microbiology team, discussed DNA robots and how specialists at SCAMT are using them to develop a new system for express diagnostics.


  • Picture of the Week: Nanoparticles Based on Hyaluronic Acid

    Such particles can potentially be used for targeted drug delivery.


  • Scientists Create New IR-Activated Coating for Local Drug Delivery

    The coating is based on active substances, in particular, bone morphogenetic protein 2 (BMP-2), loaded into the titania layer and modified by polypyrrole. If this coating is fabricated on the implant surface, it is possible to accelerate the injury recovery and to control this process using infrared radiation (IR).


  • ITMO Scientists are on the Verge of Designing Pathogen-Based Drug Delivery Systems

    Researchers have created drug delivery systems based on hollow calcium carbonate particles, resembling the E. coli K12 bacterium in shape. This approach may potentially allow further development of carriers that can be perceived by pathogens as their own cells, integrate into bacterial biofilms, and release a therapeutic agent in a controlled manner, when necessary.


  • Pharmacological Constructor: Scientists Propose Method for Synthesising Calcium Carbonate Particles with Different Geometry for Targeted Drug Delivery

    A group of scientists from ITMO’s Faculty of Physics and Engineering in collaboration with their colleagues from the First Pavlov State Medical University of St. Petersburg and Tel Aviv University conducted a complex analysis of the growth conditions of porous particles of calcium carbonate of various morphology that can be used for delivering bioactive substances to cells and tissue. The samples were tested on a model of glioma cells. The results were published in ACS Sustainable Chemistry and Engineering. ITMO.NEWS contacted Landysh Fatkhutdinova, a Master’s student at ITMO’s Faculty of Physics and Engineering, and her research advisor Mikhail Zyuzin, and learned about the prospects of the research’s application in biology and medicine.


  • ITMO Researchers Develop Universal System for Delivery and Release of Antitumor Drugs Using Infrared Radiation

    Oleksii Peltek, a Master’s student at ITMO University’s Faculty of Physics and Engineering, and his scientific advisor Mikhail Zyuzin have presented their research in the field of cell technologies. The scientists conducted a range of experiments on targeted delivery and non-invasive release of anticancer drugs for enabling effective treatment of malignant tumors. It is planned that going forward, the smart delivery systems they developed will be tested on animal models in vivo. The research results have been recently published in a leading international journal Biomaterials Science.


  • Scientists Create New Magnetic Nanosphere For Efficient Drug Delivery

    Researchers from ITMO University created a new kind of magnetic nanospheres for drug delivery. Due to the unique combination of synthesis methods, the size of these magnetite-based nanospheres can be easily regulated. At the same time, the nanospheres are not damaging to cells. The scientists proved the new material’s effectiveness in a range of experiments on dissolving model plasma clots. The results were published in Applied Materials & Interfaces.